It's more about finding your niche audience than about compromising your work. There's a big difference between the two. This is what I have learned after taking business classes and putting my learning into practice for over a year now.
As a child, I believed in creating what was from pure inspiration and not changing just to fit in a box. Not much has changed in my rational. There are people who are looking for art that speaks to their unique values and experiences, but have trouble finding it. This is precisely why it's important for an artist to create work from his or her own unique vision. Many galleries and art institutions only cater to a segment of the people.
Also in 2013 of this Information Age our place in the culture as individuals is changing. Because of the Internet, anyone with access can have a voice and make an impact. As a culture, we used to have to wait for approval from authorities to publish a book, exhibit our art, get an education, get funding, and the list goes on. Over and over we see that everyday people publish a blog or video and change the course of events in a major political election or a talent search, etc.
With this in mind, let us all continue to make our unique contribution.